Adrenal Dysfunction

The adrenal glands, located on the top of each kidney, are responsible for the production of sex hormones (estrogen and testosterone) as well as cortisol (the stress hormone). These hormones are essential to proper body function and are the primary source of estrogen and testosterone in men and women after reaching middle age.

Adrenal gland disorders affect the production of these hormones. For example, Cushing’s syndrome causes the body to create too much cortisol while in Addison’s disease, the glands do not make enough. Additionally, conditions such as congenital adrenal hyperplasia and hyperaldosteronism may also cause the adrenal glands to make too much or too little of the essential hormones created in the adrenal glands. Causes of adrenal gland disorders can include genetic mutations, tumors, infections, certain medications, or problems with other glands.

Symptoms of adrenal gland disorders vary significantly between conditions, but may include:

  • Obesity, especially around the upper abdomen and face
  • Skin problems
  • Hypertension or hypotension
  • Depression or other mood disorders
  • Excess facial hair in women
  • Menstrual irregularity
  • Early puberty
  • Headache
  • Brittle bones
  • Weight loss
  • Weakness
  • Fatigue
  • Craving for salt
  • Nausea or vomiting

Depending on the condition, treatment may include surgery to remove tumors or hormone replacement therapy.

Thyroid Dysfunction

Hormones triiodothyronine (T3) and thyroxine (T4) are produced by the thyroid and responsible for the regulation of metabolism and bone growth as well as protein synthesis. About ten million Americans suffer from hypothyroidism, and nearly half don’t know they have it! Disruption in the thyroid hormones is generally caused by one of two things: ongoing inflammation of the thyroid (frequently autoimmune thyroiditis or Hashimoto’s thyroiditis wherein the patient’s immune system causes the inflammation), or hypothyroidism, which is caused by “medical treatments” such as the removal of all or part of the thyroid due to cancer or other medical conditions like goiter.

Symptoms of hypothyroidism include:

  • Fatigue
  • Weakness
  • Cold intolerance
  • Decreased libido
  • Trouble remembering things
  • Depression
  • Irritability
  • Weight gain or difficulty losing weight
  • Hair loss
  • Coarse, dry hair
  • Dry, rough, pale skin
  • Muscle pain
  • Constipation
  • Abnormal menstrual cycles

Not every patient will experience all of these symptoms, and they may also vary significantly in severity between individuals. Hypothyroidism can typically be diagnosed by a test known as a thyroid panel that checks the levels of thyroid hormones in the blood.

Although rarely life-threatening, hypothyroidism can benefit from a personalized approach, which may greatly improve a patient’s well-being and overall success with prescribed thyroid replacement therapy. Traditionally, patients have been treated with levothyroxine (synthetic T4), although some patients don’t respond fully to this alone and may also require synthetic T3. This can be problematic though due to the swift absorption of this drug by the body resulting in higher than normal T3 levels creating a myriad of problems including heart palpitations.

For patients who require Natural Thyroid rather than synthetic thyroid replacement, Pure Pharmacy can help. We can formulate many forms and strengths of Natural Thyroid not available in standard pharmacies. Additionally, we can combine pure T3 and T4 powders to exact strengths for individual needs, eliminating unnecessary additives and unwanted side effects.

Subclinical Hypothyroidism

People with Mild Thyroid Failure “subclinical hypothyroidism” have symptoms of thyroid deficiency, although lab tests may indicate their thyroid function is “normal”. In 2003, the normal range for Thyroid Stimulating Hormone (TSH) was adjusted from 0.5-5.0 to 0.3-3.0 as the American Academy of Clinical Endocrinologists acknowledged that symptoms of hypothyroidism frequently occurred in patients with “normal” lab values. Many patients with thyroid dysfunction have tried synthetic thyroid hormones, such as levothyroxine and liothyronine, and have found that natural thyroid is the only form that works adequately for them. Compounded Natural Thyroid is an option when commercial products are unavailable.

Compounded Thyroid Preparation

Many patients have tried synthetic thyroid hormones, such as levothyroxine and liothyronine, and have found that Natural Thyroid is the only form that works adequately for them, reporting that they simply do not feel as well when they take levothyroxine alone or with liothyronine.

Commercially available tablets contain fillers and excipients that may not be tolerated by all patients. When we compound customized dosages, we have the ability to omit any problem-causing inactive ingredients and substitute non-reactive fillers. We welcome your questions and the opportunity to help your patients.

Certain forms and strengths of Natural Thyroid are available only through compounding pharmacies. In addition, we can blend T4 and T3 pure powders in a specific ratio by prescription.

For more information on adrenal or thyroid dysfunctions or to schedule an appointment, please don’t hesitate to contact us today.